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PDD Graph: Bridging Electronic Medical Records and Biomedical Knowledge Graphs via Entity Linking

机译:pDD图:桥接电子病历和生物医学知识   图表通过实体链接

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摘要

Electronic medical records contain multi-format electronic medical data thatconsist of an abundance of medical knowledge. Facing with patient's symptoms,experienced caregivers make right medical decisions based on their professionalknowledge that accurately grasps relationships between symptoms, diagnosis andcorresponding treatments. In this paper, we aim to capture these relationshipsby constructing a large and high-quality heterogenous graph linking patients,diseases, and drugs (PDD) in EMRs. Specifically, we propose a novel frameworkto extract important medical entities from MIMIC-III (Medical Information Martfor Intensive Care III) and automatically link them with the existingbiomedical knowledge graphs, including ICD-9 ontology and DrugBank. The PDDgraph presented in this paper is accessible on the Web via the SPARQL endpoint,and provides a pathway for medical discovery and applications, such aseffective treatment recommendations.
机译:电子病历包含多种格式的电子病历,其中包含丰富的医学知识。面对患者的症状,有经验的护理人员会根据他们的专业知识做出正确的医疗决策,这些知识可以准确把握症状,诊断和相应治疗方法之间的关系。在本文中,我们旨在通过建立一个大型高质量的异质图来链接这些关系,这些异质图将EMR中的患者,疾病和药物(PDD)链接起来。具体来说,我们提出了一个新颖的框架,可以从MIMIC-III(重症监护III的医疗信息集市)中提取重要的医学实体,并将它们与现有的生物医学知识图谱自动链接,包括ICD-9本体论和DrugBank。本文中介绍的PDDgraph可通过SPARQL端点在Web上访问,并为医学发现和应用(例如有效的治疗建议)提供了途径。

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